Single-cell Atlas of Common Variable Immunodeficiency

1. Steady-state B cells

2. Activated PBMCs

Steady-state B cells

scRNA-seq

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Fully processed .h5ad single-cell object for steady-state B cells (scRNA-seq, Smart-seq2) with raw data in .raw attribute

scATAC-seq

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Fully processed .h5ad single-cell object for steady-state B cells (scATAC-seq) from binarised single-cell accessibility matrix with raw binarised accessibility values in .raw attribute

scBS-seq

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Matrix of raw methylation values in pseudobulks aggregated by B cell state and donor in steady-state B cells

Activated PBMCs

scRNA-seq

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Fully processed .h5ad single-cell object for activated PBMCs (scRNA-seq, 10X) with raw data in .raw attribute