Single-cell Atlas of Common Variable Immunodeficiency

Steady-state B cells

scBS-seq

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Matrix of raw methylation values in pseudobulks aggregated by B cell state and donor in steady-state B cells

scATAC-seq

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Fully processed .h5ad single-cell object for steady-state B cells (scATAC-seq) from binarised single-cell accessibility matrix with raw binarised accessibility values in .raw attribute

scRNA-seq

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Fully processed .h5ad single-cell object for steady-state B cells (scRNA-seq, Smart-seq2) with raw data in .raw attribute

Activated PBMCs

Twins
scRNA-seq

Expanded cohort
CITE-seq

Twins scRNA-seq
Validation cohort CITE-seq
Interactive viewer Download h5ad data

Fully processed .h5ad single-cell object for activated PBMCs (scRNA-seq, 10X) with raw data in .raw attribute

Interactive viewer Download h5ad data

Fully processed .h5ad single-cell object for activated PBMCs (scRNA-seq, 10X) with raw data in .raw attribute